代表著作

  • Geng Y, Liu C, Cai Q, Luo Z, Miao H, Shi X, Xu N, Fung CP, Choy TT, Yan B, Li N, Qian P, Zhou B, Zhu G. Crystal structure of parallel G-quadruplex formed by the two-repeat ALS- and FTD-related GGGGCC sequence. Nucleic Acids Res. 2021 Jun 4;49(10):5881-5890.

  • Weng J, Yang Y, Song D, Huo R, Li H, Chen Y, Nam Y, Zhou Q, Jiao Y, Fu W, Yan Z, Wang J, Xu H, Di L, Li J, Wang S, Zhao J, Wang J, Cao Y. Somatic MAP3K3 mutation defines a subclass of cerebral cavernous malformation. Am J Hum Genet. 2021 May 6;108(5):942-950.

  • Lau SF, Fu AKY, Ip NY. Cytokine signaling convergence regulates the microglial state transition in Alzheimer's disease. Cell Mol Life Sci. 2021 May;78(10):4703-4712.

  • Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL. Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol Psychiatry. 2021 Apr;26(4):1346-1360.

  • Park C, Chen X, Tian CL, Park GN, Chenouard N, Lee H, Yeo XY, Jung S, Tsien RW, Bi GQ, Park H. Unique dynamics and exocytosis properties of GABAergic synaptic vesicles revealed by three-dimensional single vesicle tracking. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2022133118.

  • Wu X, Ganzella M, Zhou J, Zhu S, Jahn R, Zhang M. Vesicle Tethering on the Surface of Phase-Separated Active Zone Condensates. Mol Cell. 2021 Jan 7;81(1):13-24.e7.

  • Wang Y, Fu WY, Cheung K, Hung KW, Chen C, Geng H, Yung WH, Qu JY, Fu AKY, Ip NY. Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2020810118.

  • Yu X, Zhao Q, Li X, Chen Y, Tian Y, Liu S, Xiong W, Huang P. Deafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 binding. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29894-29903.

  • Wu S, Nguyen LTM, Pan H, Hassan S, Dai Y, Xu J, Wen Z. Two phenotypically and functionally distinct microglial populations in adult zebrafish. Sci Adv. 2020 Nov 18;6(47):eabd1160.

  • Ouyang L, Chen Y, Wang Y, Chen Y, Fu AKY, Fu WY, Ip NY. p39-associated Cdk5 activity regulates dendritic morphogenesis. Sci Rep. 2020 Oct 30;10(1):18746.

  • Lau SF, Cao H, Fu AKY, Ip NY. Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer's disease. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25800-25809.

  • Qin Z, Chen C, He S, Wang Y, Tam KF, Ip NY, Qu JY. Adaptive optics two-photon endomicroscopy enables deep-brain imaging at synaptic resolution over large volumes. Sci Adv. 2020 Sep 30;6(40):eabc6521.

  • Zhou X, Chen Y, Ip FCF, Lai NCH, Li YYT, Jiang Y, Zhong H, Chen Y, Zhang Y, Ma S, Lo RMN, Cheung K, Tong EPS, Ko H, Shoai M, Mok KY, Hardy J, Mok VCT, Kwok TCY, Fu AKY, Ip NY. Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population. Alzheimers Dement (Amst). 2020 Aug 5;12(1):e12074.

  • Oldrini B, Vaquero-Siguero N, Mu Q, Kroon P, Zhang Y, Galán-Ganga M, Bao Z, Wang Z, Liu H, Sa JK, Zhao J, Kim H, Rodriguez-Perales S, Nam DH, Verhaak RGW, Rabadan R, Jiang T, Wang J, Squatrito M. MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas. Nat Commun. 2020 Aug 4;11(1):3883.

  • Chen K, Yang R, Li Y, Zhou JC, Zhang M. Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubules. J Cell Biol. 2020 Aug 3;219(8):e201910053.

  • Yue L, Wan R, Luan S, Zeng W, Cheung TH. Dek Modulates Global Intron Retention during Muscle Stem Cells Quiescence Exit. Dev Cell. 2020 Jun 22;53(6):661-676.e6.

  • Au FKC, Hau BKT, Qi RZ. Nek2-mediated GAS2L1 phosphorylation and centrosome-linker disassembly induce centrosome disjunction. J Cell Biol. 2020 May 4;219(5):e201909094.

  • Lau SF, Chen C, Fu WY, Qu JY, Cheung TH, Fu AKY, Ip NY. IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer's Disease. Cell Rep. 2020 Apr 21;31(3):107530.

  • Chen X, Wu X, Wu H, Zhang M. Phase separation at the synapse. Nat Neurosci. 2020 Mar;23(3):301-310.

  • Lok TM, Wang Y, Xu WK, Xie S, Ma HT, Poon RYC. Mitotic slippage is determined by p31comet and the weakening of the spindle-assembly checkpoint. Oncogene. 2020 Mar;39(13):2819-2834.